Each area of the game is an endless turn-based battle in which you'll have to defeat dozens of enemies instead of the standard handful, and try to go as far as possible.
In Wacky Spores: The Chase you don't just select your targets like other turn-based games, you manually aim weapons and abilities so that you can maximize the enemies hit and the damage done.
Winning a battle requires simple tactical choices like deciding which character to bring in the battlefield, choosing the right weapon for the right monster, deciding when to disable enemies and when to just attack, using items and abilities, etc.
When it's the enemies turn they will move, attack and cast in real time and you'll move the three characters together to dodge bullets.
In every battle you collect coins by picking them up or by completing quests. The more coins you get the faster you level up unlocking more characters, weapons, artifacts etc, which in turn will push you further in every battle.